ZHOU Hong-bi, LI Le-xiang
(Wison Engineering CO LTD, Zhengzhou 450000, China)
Abstract: The electrochemical behaviour of shikonin was investigated on a glassy carbon electrode in an acetate buffer (pH=3.98) solution using cyclic voltammetry. Shikonin gives a pair of redox peaks by the absorption-controlled process. The experimental conditions were optimized for the determination of shikonin and the square-wave anodic peak currents were linearly related to the shikonin concentrations in the range from 2.08×10−8 to 1.82×10−6 mol/L with a correlation coefficient of 0.998. Using the established method without pretreatment and pre-separation, shikonin in herbal drug Gromwell Root was determined with satisfactory result.
Key words: Shikonin; Electrochemical; Determination
E-mail: zhouhongbi@wison.com.cn
Analysis and Testing Technology and Instruments, Vol. 17, No. 3, 2011,160-163
