CO2-Promoted Direct Acylation of Amines and Phenols by the Activation of Inert Thioacid Salts

Abstract Herein a carbon dioxide-promoted synthetic approach for the direct amidation between unactivated thioacid salts and amines under mild conditions was developed for a wide range of substrates .The method afforded amides in good to excellent yields under transition-metal-free and activation-reagent-free conditions , in sharp contrast to ea...