LIU Zhi-qi1, WANG Ming-gang1, XUE Ming 2 ,LI Jian-yong3
(1. Academy of Life Science and Engineering, Lanzhou University of Technology, 730050 Lanzhou; 2.Department of Pharmacology, School of Basic Medicine, Capital Medical University, Beijing 100069; 3. Lanzhou Institute of Animal Science and Veterinary Pharmaceutics, Chinese Academy of Agricultural Sciences, 730050 Lanzhou )
Abstract: Cyclodextrin (CD) has been widely used for the separation and analysis of chiral enantiomers due to its special structural features and chiral environment. In this paper the application and progress in the research of CD and its derivatives in the analysis of chiral drugs by various chromatographic, mass spectrometric and NMR methods in recent years are reviewed.
Key words: cyclodextrin; chiral drug; chiral compound; separation and analysis
E-mail: xuem@ccmu.edu.cn
Analysis and Testing Technology and Instruments, Vol. 18, No. 1, 2012,14-18