LIU Jian-ming1,2, WANG Jing-fang1, YUE, Yuan-yuan1, LIU Mu-wen1, ZHUO, Ke-lei1, XIA, Chun-gu2*
(1 Chemistry and Environmental Science, Henan Normal University, Xinxiang, Henan 453007, PR China. 2 State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 73000, P. R. China)
Abstract: An efficient carbonylative Sonogashira coupling reaction of aryl iodides with terminal alkynes were carried out in presence of an catalytic system in situ prepared from Pd2(dba)3 and triethylamine, achiving the corresponding products α,β-alkynyl ketones with up to 95% of yield under mild conditions. This developed catalytic system demonstrates a broad tolerance of alkynes and aryl iodides substrates with various substituents during the carbonlative Sonogashira coupling reaction.
Key words: Pd2(dba)3; α, β-alkynyl ketones; carbonylative Sonogashira coupling reaction;
E-mail: cgxia@licp.cas.cn
Journal of Molecular Catalysis, Vol. 25, Issue 1, 2011, 17~23
