Zhu Qiming^{1, 2}, Huang Hanmin¹*, Xia Chungu¹

(1. State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, P. R. China; 2. Graduate School of the Chinese Academy of Sciences, Beijing 100039, P. R. China )

Abstract: A series of chiral diamines with novel rigid structure have been successfully applied in the Diels-Alder reaction. The effect of reaction conditions such as Brønsted acid, temperature, solvent and different substitutes on the diamines was also extensively investigated. The results showed that the Diels-Alder reaction processed smoothly with high yield and moderateenantiomeric excess under the optimized reaction conditions.

Key words: Chiral diamine; Brønsted acid; Diels-Alder reaction; Asymmetric catalysis

E-mail: hmhuang@licp.cas.cn

Journal of Molecular Catalysis, Vol. 25, Issue 1, 2011, 6~10