LIU Yong-wei1, LI Zheng-ning1,2, CHEN Hui-ying3, JIANG Lan1
(1. College of Environmental and Chemical Engineering, Dalian University, Dalian 116622, China; 2.Liaoning Key Laboratory of Bioorganic Chemistry, Dalian University, Dalian 116622, China; 3.College of Life Science, Dalian Nationalities University, Dalian 116605, China)
Abstract: Benzyl ethers were prepared in good yields via the reaction of O-benzyl isourea with alcohols or phenols in the presence of BF3·Et2O. The mild reaction conditions and the availability of the reagent for the reaction provide an alternative method for the protection of hydroxyl group in alcohol and phenol in organic synthesis.
Key words: isourea; etherization; alcohol; benzylation.
E-mail: znli@dl.cn
Journal of Molecular Catalysis, Vol. 25, Issue 3, 2011, 250~253
