DUAN Zhengchao^1*, WANG Lianzhi¹, HU Xiangping^2*, ZHENG Zhuo²

(1.Hubei University for Nationalities, Enshi 445000, China; 2.Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023,China)

Abstract: Chiral monodentate phosphoramidite ligands have been successfully used in the rhodium-catalyzed asymmetric hydrogenation of various enamides,beta-dehydroamino acid esters, alfa-dehydroamino acid esters and dimethyl itaconate. Up to 96% ee for enamides, 86% ee for beta-dehydroamino acid esters, 75% ee for dimethyl itaconate and 95% ee for alfa-dehydroamino acid esters were obtained.

Key words: Monodentate Phosphoramidite Ligands; Enamides; beta-Dehydroamino Acid Esters; alfa-Dehydroamino Acid Esters; Asymmetric Hydrogenation

E-mail: zhengz@dicp.ac.cn

Journal of Molecular Catalysis, Vol. 26, Issue 4, 2012,328-332