Abstract
Chiral pillar[n]arenes have shown great research value and application prospect in construction of chiral materials and chiral applications, due to their inherent planar chiral configurations, chiral recognition ability, easy modification and highly symmetric hydrophobic cavity. This review systematically summarized the conformation inversion factors of planar chiral pillar[5]arenes (pR/pS), such as solvents, temperature, substituent size, alkyl chains, chiral and achiral guest molecules. We firstly introduced the applications of chiral pillar[n]arenes for constructing chiral materials and pointed out that planar conformation inversion showed a great potential role in constructing chiral materials. Then, we mainly concluded the chiral applications of chiral and planar chiral pillar[n]arenes like chiral enantiomer analysis by circular dichroism, electrochemistry or chiral fluorescence sensing. From this review, we found that the inherent planar chiral conformation of chiral pillar[n]arenes have played a very important role in chiral field in the future. (C) 2022 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.
Chiral pillar[n]arenes have shown great research value and application prospect in construction of chiral materials and chiral applications, due to their inherent planar chiral configurations, chiral recognition ability, easy modification and highly symmetric hydrophobic cavity. This review systematically summarized the conformation inversion factors of planar chiral pillar[5]arenes (pR/pS), such as solvents, temperature, substituent size, alkyl chains, chiral and achiral guest molecules. We firstly introduced the applications of chiral pillar[n]arenes for constructing chiral materials and pointed out that planar conformation inversion showed a great potential role in constructing chiral materials. Then, we mainly concluded the chiral applications of chiral and planar chiral pillar[n]arenes like chiral enantiomer analysis by circular dichroism, electrochemistry or chiral fluorescence sensing. From this review, we found that the inherent planar chiral conformation of chiral pillar[n]arenes have played a very important role in chiral field in the future. (C) 2022 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.
Keywords Plus：PLANAR-CHIRALITYDIASTEREOSELECTIVE SYNTHESISMOLECULAR RECOGNITIONFLUORESCENCEARENECONSTRUCTIONCOMPLEXATIONTEMPERATUREDERIVATIVESCONVERSION
Published in CHINESE CHEMICAL LETTERS，Volume33；10.1016/j.cclet.2021.12.010，AUG 2022