Abstract
Phosphine-containing porous organic polymers (phosphine-POPs) are a kind of potential catalyst support for alkene hydroformylation. However, the synthesis of phosphine-POPs with strong pi-acceptor is still a challenge. Herein, we report the synthesis of phosphine-POPs with different pi-acceptor properties [POLP(Pyr)3, CPOL-BPa&PPh3-15, and CPOL-BP&PPh3-15] and evaluated their performances as ligands to coordinate with Rh(acac)(CO)2 for hydroformylation of alkenes. We found that the Rh center with stronger pi-acceptor phosphine-POPs showed better catalytic performance. Rh/CPOL-BPa&PPh3-15 with strong pi-acceptor bidentate phosphoramidites showed obviously higher activity and regioselectivity (TON = 7.5 x 103, l/b = 26.1) than Rh/CPOLBP&PPh3-15 (TON = 5.3 x 103, l/b = 5.0) with weaker pi-acceptor bidentate phosphonites. Particularly, the TON of the hydroformylation reached 27.7 x 103 upon using Rh/POL-P(Pyr)3 which possessed tris(1-pyrrolyl)phosphane coordination sites. Overall, our study provides an orientation to design phosphine-POPs for hydroformylation reactions.

Keywords Plus:RHODIUMLIGANDSINDUSTRIALALKYLARYL

Published in JOURNAL OF ORGANIC CHEMISTRY;10.1021/acs.joc.2c02105,NOV 2022