Abstract
A novel amino-functionalized zinc ferrite nanoparticles/MXene (ZnFe2O4-NH2/MXene composite which consist of ZnFe2O4 -NH2 and single/few layers MXene was designed and synthesized as an efficient extrac-tant for analysis of vitamin B 2 in rice first combined with ultrahigh-performance liquid chromatography -tandem mass spectrometry (UPLC-MS/MS). As a result, the single/few layer MXene was tightly attached to the spherical ZnFe2O4 -NH2 nanoparticles by electrostatic self-assembly interaction, which present large specific surface area and fast mass transfer rate. The relevant experimental parameters, including the pH of the solution, extraction time, adsorbent amount, desorption solvent, desorption solvent volume and desorption time were investigated and optimized. Under optimum conditions, the ZnFe2O4-NH2/MXene composite exhibited excellent selectivity and adsorption capacity for vitamin B 2 through hydrogen bond-ing interactions and the metal-pi complexation interaction. The adsorption kinetics, isotherms, and ther-modynamic studies were systemically investigated to evaluate the adsorption mechanism and charac-teristics, which ascribed to chemical adsorption, monolayer adsorption and a spontaneous endothermic process. Furthermore, the performance of the proved method was validated with the good linear corre-lation coefficient ( r = 0.999), low limit of detection (0.86 ng center dot mL -1) and the limit of quantification (2.98 ng center dot mL -1), satisfactory recoveries (81.7-102.5%) and reasonable accuracy (RSD < 7.8%). The theoretical and technological underpinning for investigating the kinship amongst vitamin alterations and the degree of rice storage was set using this suggested approach to assess vitamin B 2 in rice from various years. (c) 2023 Elsevier B.V. All rights reserved.

Keywords Plus：SOLID-PHASE EXTRACTIONRIBOFLAVINNANOPARTICLESMXENESFOOD

Published in JOURNAL OF CHROMATOGRAPHY A，Volume1693；10.1016/j.chroma.2023.463881，MAR 29 2023